The Enzyme-Modified Neutral Comet (EMNC) Assay for Complex DNA Damage Detection
نویسندگان
چکیده
منابع مشابه
A modified alkaline Comet assay for in vivo detection of oxidative DNA damage in Drosophila melanogaster.
Modifications to the alkaline Comet assay by using lesion-specific endonucleases, such as formamidopyrimidine-DNA glycosylase (FPG) and endonuclease III (ENDOIII, also known as Nth), can detect DNA bases with oxidative damage. This modified assay can be used to assess the genotoxic/carcinogenic potential of environmental chemicals. The goal of this study was to validate the ability of this modi...
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ژورنال
عنوان ژورنال: Methods and Protocols
سال: 2021
ISSN: 2409-9279
DOI: 10.3390/mps4010014